Retatrutide Peptide
10mg · Lyophilized Powder · ≥98%
Retatrutide is a triple agonist targeting GIP, GLP-1, and glucagon receptors simultaneously — the first peptide to engage all three pathways. Early phase clinical trial results published in the New England Journal of Medicine showed dose-dependent responses across metabolic parameters. The triple-agonist mechanism is a novel approach that goes beyond existing dual-agonist compounds.
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Retatrutide
$64.99
Research Use Only
FOR RESEARCH USE ONLY. Products sold by Healthy Aminos are intended strictly for in-vitro research and laboratory use. Not for human or animal consumption. Not FDA approved. By purchasing from Healthy Aminos, the buyer acknowledges that these products are not intended to diagnose, treat, cure, or prevent any disease. All products are sold as reference standards and research chemicals only.
Compound Specifications
Research Context
Triple agonist engaging GIP receptor, GLP-1 receptor, and glucagon receptor. The glucagon component adds thermogenic and lipolytic signaling pathways not present in GLP-1-only or dual GIP/GLP-1 compounds.
View published researchRetatrutide Published Research
Retatrutide (LY3437943) is a triple agonist peptide targeting GIP, GLP-1, and glucagon receptors simultaneously. It represents a novel approach in incretin-based research, combining three receptor activities in a single molecule. Phase 2 clinical trial results were published in 2023.
Triple Receptor Agonism
Published research has characterized retatrutide's activity at three distinct receptors: GIP, GLP-1, and glucagon receptors. Studies have examined the relative potency at each receptor and the theoretical additive or synergistic effects of combined receptor activation. The glucagon receptor component distinguishes it from dual agonists like tirzepatide.
References
Phase 2 Clinical Research
Phase 2 clinical trial data published in the New England Journal of Medicine examined retatrutide across multiple dose levels in a 48-week randomized, double-blind, placebo-controlled trial. The study enrolled 338 participants and examined metabolic and body composition endpoints at 12mg dose levels. This represents the most advanced published data on a triple-agonist peptide.
References
The studies referenced above are presented for informational purposes only and do not constitute medical claims. All Healthy Aminos products are sold for research use only and are not intended for human consumption.
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Research Use Only
FOR RESEARCH USE ONLY. Products sold by Healthy Aminos are intended strictly for in-vitro research and laboratory use. Not for human or animal consumption. Not FDA approved. By purchasing from Healthy Aminos, the buyer acknowledges that these products are not intended to diagnose, treat, cure, or prevent any disease. All products are sold as reference standards and research chemicals only.