Compound Profiles
BPC-157: Published Research on Body Protection Compound-157
Healthy Aminos Research Team · · 5 min read
Background
BPC-157 is a synthetic pentadecapeptide derived from a segment of human gastric juice protein. First characterized in the early 1990s, it has been studied in laboratory and animal models across more than 100 published papers in peer-reviewed journals.
Molecular Properties
BPC-157 consists of 15 amino acids with the sequence Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val. Its molecular weight is 1419.55 Da (CAS: 137525-51-0). It is stable in human gastric juice — a property unusual for peptides, which typically degrade rapidly in acidic environments.
Published Research Areas
Research has examined BPC-157 in several model systems:
- Gastrointestinal mucosal integrity in animal models
- Tendon and ligament healing in rat models
- Muscle injury recovery in animal models
- Interactions with growth factor signaling pathways including FAK-paxillin and VEGF expression
- Neuroprotection models examining the NO system
Key Publications
The majority of published BPC-157 research comes from the laboratory of Dr. Predrag Sikiric at the University of Zagreb, with studies published in journals including the Journal of Physiology, Life Sciences, and Regulatory Peptides.
Current Limitations
Most published studies are preclinical (animal models or in-vitro). Large-scale human clinical trials have not been published as of 2026. This is an important consideration when evaluating the research literature.
Research Use Only
FOR RESEARCH USE ONLY. Products sold by Healthy Aminos are intended strictly for in-vitro research and laboratory use. Not for human or animal consumption. Not FDA approved. By purchasing from Healthy Aminos, the buyer acknowledges that these products are not intended to diagnose, treat, cure, or prevent any disease. All products are sold as reference standards and research chemicals only.